Knowledge Transfer in Support of the Development of Oxygen Concentrators in Emergency Settings During the COVID-19 Pandemic

The COVID-19 pandemic simultaneously disrupted supply chains and generated an urgent demand in medical infrastructure. Among personal protective equipment and ventilators, there was also an urgent demand for chemical oxygen. As devices to purify oxygen could not be manufactured and shipped rapidly enough, a simple and accessible oxygen concentrator based on pressure swing adsorption was developed at ETH Zurich in spring 2020. Instead of building devices locally and shipping them, it was decided to educate others in need of oxygen. The implementation encompassed education on process chemistry, material choice, and assembly and optimization of the concentrator and was realized using synchronous teaching tools, such as video call, and asynchronous ones, such as a website and video streaming. The project gained traction and interaction with engineering teams from universities and non-Governmental Organizations (Red Cross and the UN Development Program) in developing countries and emerging market economies, including Ecuador, Mexico, Somalia, and Peru. At the end of the project, the teams were surveyed regarding their experience in the educative knowledge transfer. It was reported that the learning experience prepared these groups well to build the device and to teach others as well. Major challenges were accessing some parts of the device and optimizing its performance. While synchronous communication is expected to be a very effective teaching method, the survey results showed that explanations via a website and video streaming have contributed the most to the implementation of the oxygen concentrator and thereby provide autonomous and sustainable education tools. © 2023 The Authors. Published by American Chemical Society and Division of Chemical Education, Inc.

Instrumental Analysis Experience-Based Teaching before and during the COVID-19 Pandemic: Challenges and Opportunities

The COVID-19 outbreak represented a remarkable challenge in universities and colleges since it forced the transition from a face-to-face model in classrooms and laboratories to a remote, online model using computers, tablets, and cell phones. In Mexico and other Latin American countries, the return to educational activities was a slow-paced process. The lack of presential activities had a deep impact on education, particularly in under- and graduate Chemistry courses, where laboratory work allows students to develop skills and abilities by applying their knowledge to solve experimental problems. As a consequence, institutional and personal efforts were put together to overcome this situation. These efforts led to remarkable experiences and outcomes with high educational value. This work presents experiences and outcomes of the Instrumental Analysis course offered in the Chemistry Clinical Biologist bachelor program throughout three nonconsecutive semesters, each time on different contexts, to describe the challenges faced, and the emerging opportunities from the experience throughout the pandemic. Each experience is described in a case study. Case 1 exemplifies a regular, pre-COVID-19 semester, in 2019, in a fully face-to-face teaching modality. Case 2 describes a semester in the middle of the COVID-19 crisis in 2020, in a 100% online teaching modality. Finally, Case 3 presents a semester with low prevalence of COVID-19 cases, using a hybrid modality, in 2021. Our observations suggest significant differences related to the knowledge integration process when laboratory work was interrupted, and provide evidence about how online activities impacted the learning process in experimental chemistry courses. © 2023 American Chemical Society and Division of Chemical Education, Inc.

Teaching Microextraction Techniques During COVID-19 Pandemic through Remote Lab Strategy

Since the appearance of the COVID-19 pandemic and its subsequent stage, the changes produced in the chemistry teaching process have allowed educators to use a wide range of strategies, methodologies, and tools to promote student learning. To carry out laboratory practices, some strategies reported include the use of simulators and educational software, as well as the development of remote lab activities. In recent years, the teaching of microextraction techniques and the greening of the sample treatment process represent an important topic in instrumental analytical chemistry courses, incorporating green chemistry topics in the curricula. In this context, a hands-on activity through a kit of materials, equipment, and reagents delivered to students for teaching microextraction techniques during the pandemic's learning conditions is presented. The activity was designed to extract a food coloring dye applying four microextraction techniques, including solid-phase extraction (SPE), solid-phase microextraction (SPME), in-tube solid-phase microextraction (IT-SPME), and micro polymeric magnetized bar adsorptive extraction (μ-PMBAE). Finally, for quantitative analysis, a colorimetry and absorbance-based experiment through image acquisitions and RGB analysis was used. The experiments were applied as extracurricular activities, and students' feedback was fruitful due to the enthusiasm that it produced in them to carry out laboratory tasks after so much time of confinement. Among the successful points of the activity, it is possible to mention the ease of carrying out the experiments from home and the application of green sample treatment techniques that minimize the use of materials and reagents. © 2023 American Chemical Society and Division of Chemical Education, Inc.

Large Interactive Touchscreens as an Opportunity for Synchronous Hybrid Teaching during the COVID-19 Pandemic and Beyond

The year 2020 will be remembered as the year of COVID-19 and its subsequent lockdowns. The time to return to face-to-face teaching has arrived, but the shadow of the disease still hangs over teachers, students, and society. Disruption in teaching can still occur for students, or even teachers, if they are either diagnosed as COVID-19 positive or as a contact case and forced to self-isolate. In order to limit the impact of self-isolation on learning, synchronous hybrid teaching (i.e., teaching face to face to students in a classroom and to students online at the same time) was successfully implemented owing to the combination of video conference software and a large interactive touchscreen. The setup presented in this paper allows courses to be broadcast to students at home (i.e., voice, visual pedagogic support, and, more interestingly, indications handwritten by the teacher) as well as simultaneously teaching to students in the classroom face-to-face. It also allows self-isolated teachers to teach tutorials from their home to students in the classroom. This paper focuses on the use of large interactive touchscreens for synchronous hybrid teaching and its evaluation by students using a questionnaire. The key findings of this study are that students prefer synchronous hybrid teaching rather than missing a course and that synchronous hybrid teaching should only be used in case of absolute necessity. © 2023 American Chemical Society and Division of Chemical Education, Inc.

Virtual Reality as a Medium of Asynchronous Content Delivery for Teaching about Enzymes

Self-study is an integral part of chemistry learning, whereby the students consume knowledge outside of the classroom environment. The COVID-19 pandemic magnified the need for efficient methods of synchronous and asynchronous instructional content delivery worldwide. Virtual reality (VR) presents a prospective technological solution to aid asynchronous content delivery, particularly for visual subjects such as chemistry. We investigate the feasibility of using carefully designed VR-based content to assist offline instruction about enzymes and the differences in their types. They are an essential concept in biochemistry due to their comprehensiveness and the similarities between their amino acid sequences responsible for their different functions. We compare the efficacy of VR-aided self-study against self-study assisted by recorded video lectures. An experiment is conducted to simulate self-study in three scenarios, i.e., conventional text-based self-study (1) without any additional aids, (2) assisted by recorded video lectures, and (3) with VR aids. Our findings indicate that VR can assist asynchronous content consumption leading to better learning and satisfaction. © 2023 American Chemical Society and Division of Chemical Education, Inc.

Approaches to Promoting Student Engagement in Organic Chemistry Before, During, and After the COVID-19 Pandemic: Insights and Reflections

Active engagement is critical to student success in Organic Chemistry. In this paper, I trace the trajectory of student engagement in an introductory organic chemistry lecture series over the course of the COVID-19 pandemic. I detail my approach to cultivating student engagement in an online environment, evaluate the success of these approaches and discuss modifications, and recount our efforts to combat the "learned disengagement” that students exhibited upon returning to an in-person class format. Although engagement gradually dwindled over the course of online instruction, multiple interventions succeeded in maintaining a sense of classroom community in students and encouraging active participation. By building opportunities for engagement into the course structure and rewarding students who partake in class activities, I hope to once again enjoy the level of engagement that we had prior to the pandemic. © 2022 American Chemical Society and Division of Chemical Education, Inc.

"The Masked Scientist": Designing a Virtual Chemical Escape Room

Chemical escape rooms (ChEsRms) are educational games in which students use their brain, chemical knowledge, intuition, and a bit of luck to solve a mystery. At the Weizmann Institute, we have developed ChEsRms that are implemented by teachers in their classes. Since the COVID-19 pandemic stopped all the educational activities that took place in physical space, we decided to design a virtual ChEsRm (VChEsRm) that is fully conducted in digital space. We describe the design principles that characterize the VChEsRm and present the students' and teachers' perceptions of the VChEsRm and how it differs from the ChEsRm. We describe "The Masked Scientist", a VChEsRm in which students must identify a scientist using their knowledge of basic topics in the chemistry syllabus: the model of the atom, radioactivity, and the periodic table. This VChEsRm has added values, a connection to history, human rights, and sustainability, as well as interesting and surprising chemical facts related to everyday life. Since it is conducted in virtual space, it could also include experiments, procedures, and materials that are dangerous and therefore forbidden in a physical ChEsRm or that could even change the course of history. Importantly, this 90 min activity includes the VChEsRm (9 puzzles) and a 45 min follow-up session that deals with the ideas behind the puzzles. It was translated from Hebrew to Arabic and English;therefore, high school and general chemistry teachers around the world can easily use the VChEsRm in their class after reading this paper by clicking on the link. © 2022 The Authors. Published by American Chemical Society and Division of Chemical Education, Inc.

Evaluating and Improving Questions on an Unproctored Online General Chemistry Exam

Administering exams in large enrollment courses is challenging and systems in place for accomplishing this task were upended in the spring of 2020 when a sudden transformation to online instruction and testing occurred due to the COVID-19 pandemic. In the following year, when courses remained online, approaches to improve exam security included measures like using test banks and reducing the allotted time for completing exams to reduce the sharing of information. A psychometric comparison using classical test theory of an unproctored online exam with one delivered in-person indicates both have comparable reliability. However, item-level analysis demonstrates some questions performed higher in the unproctored setting, with an important variable being the item's searchability online. Revising questions to increase generalizability and reduce searchability mitigate these performance differences. Further, changing the format for questions involving calculations from multiple-choice to open response with random number generation was found to increase difficulty and item discrimination and is a viable approach for improving exam security. © 2022 Authors.

Development of Bioderived Alternatives to N95 Face Masks in a Remote Course-Based Undergraduate Research Experience

The high demand for N95 and surgical masks made of nonbiodegradable petroleum-based materials due to SARS-CoV-2 challenges the recycling industry and is proving to be unsustainable. Although woven fabric masks present a longer lifetime, they are less effective in protecting against viral particulates. Here, through an at-home course-based undergraduate research experience (CURE), we demonstrate that alginate and soy-based materials are attractive alternatives for mask fabrication: stacking calcium ion-cross-linked alginate films with soy protein isolate sheets enables electrostatic and size-exclusion filtration. State-of-the-art aerosol testing confirmed this conclusion. Furthermore, because our synthetic and at-home analytical approach relies on cheap, abundant, and food-grade materials, and requires no equipment beyond kitchenware, it has the potential to be broadly adopted for practical and educational purposes. © 2022 American Chemical Society and Division of Chemical Education, Inc.

Design and Evaluation of the BeArS@home and Slugs@home Choose-Your-Own-Adventure-Style Online Laboratory Experiments

The COVID-19 pandemic has emphasized the importance of designing effective methods for remote teaching. At the University of California, Berkeley, and the University of California, Santa Cruz, instructors adapted to the necessity of remote laboratory instruction by creating choose-your-own-Adventure-style video-based online experiments introduced to thousands of students across 11 different courses. These experiments are designed to provide students with the opportunity to make and receive feedback on experimental decisions and learn from common mistakes that they may have encountered in hands-on laboratory instruction. Students' and instructors' impressions of the online experiments and student learning outcomes in both online and traditional laboratory courses were assessed using surveys, focus groups, and interviews via a mixed-methods approach. Though most respondents (79%) did not agree that online laboratory instruction was as effective as in-person instruction, the majority agreed that the online experiments were clear and easy to follow (75%), interesting and engaging (52%), and helpful for learning about lab techniques (70%) and the concepts underlying these techniques (77%). Many also mentioned benefits of online laboratory instruction, including flexibility in scheduling and an increased focus on conceptual learning. Assessments of student learning also suggested that students who took the course online learned as much conceptually as students who had previously completed the course in-person. The results of this study highlight the positive and negative aspects of this type of interactive online laboratory instruction, which could help inform the design of future lab experiences whether they take place in an online, hybrid, or in-person environment. ©

Adaptation of Physical Chemistry Course in COVID-19 Period: Reflections on Peer Instruction and Team-Based Learning

The COVID-19 pandemic has highlighted the importance of incorporating distance learning for long periods. However, few studies have addressed strategies to overcome the limitations caused by the lockdown. In this study, we report an active learning experience on the topic of chemical kinetics, using two flipped class approaches, team-based learning (TBL) and peer instruction (PI). These methodologies have been adapted to remote learning for undergraduate students from chemistry and engineering courses. Materials (video class and bibliography) were made available, as part of the preparation for the activities. TBL and PI groups performed the active learning activity (ALA), which consisted of graphic problems about kinetics of simple order reactions. An individual post-test was applied to assess the students' performance 2 weeks after ALA. In addition, students answered a questionnaire addressing their perceptions of ALA. The methodologies did not show significant differences in students' performances. Both enabled the acquisition of soft skills. Participants of both methodologies agree that traditional in-person classes could be partially or totally replaced by ALA, corresponding to 59.6% and 9.8%, respectively. PI participants presented a better perception of their learning than TBL students did. Thus, the use of technological tools in a recontextualized way, such as the adaptation of TBL and PI to a virtual environment, proved to be very promising for the Physical Chemistry course and an opportunity to implement a methodology that places students at the center of the teaching-learning process. The active learning activities proposed in this study can integrate distance learning, even after the pandemic context. © 2022 American Chemical Society and Division of Chemical Education, Inc.

Going Virtual: Successes and Shortcomings of a Synchronous STEM Outreach Event

Gender disparities in STEM fields emerge starting in the fourth grade, when girls are less likely than boys to express interest in STEM fields. Outreach events targeted to girls during this crucial developmental period can foster a sense of belonging in STEM. Women+ Excelling More in Math, Engineering, and the Sciences (F.E.M.M.E.S.) is a student-run organization at the University of Michigan that organizes STEM outreach events for children in the fourth grade and older. During the COVID-19 pandemic, F.E.M.M.E.S. transitioned events to a virtual setting. This manuscript describes the design of the virtual program, which included hands-on activities, live virtual demonstrations, and engaged role models. This manuscript also presents survey results from participants and volunteers to demonstrate the overall success of the virtual program and areas for improvement. ©

The Development, Use, and Evaluation of Digital Games and Quizzes in an Introductory Course on Organic Chemistry for Preservice Chemistry Teachers

Due to the COVID pandemic, the introductory course on organic chemistry was developed and conducted as an online course. To ensure methodical variety in this course, educational games and quizzes have been developed, used, and evaluated. The attendance of the course, and therefore also the use of the quizzes and games, was voluntary. The quizzes' main goal was to give the students the opportunity to check whether they had memorized the knowledge needed in the course. Another goal was to make transparent which knowledge the students should memorize by rote. The evaluation shows that the students had not internalized all knowledge which they should apply in several tasks on organic chemistry. They answered multiselect questions in general less well than single-select questions. The games should combine fun with learning. The evaluation of the games shows that the students rated them very well. The students used those games again for their exam preparation, as the monitoring of accessing the games showed. Students' experiences with using electronic devices in general or for quizzes and games have also been evaluated, because their experience could influence the students' assessment of the quizzes and games used in our study. However, the students used electronic devices regularly and should therefore be technically competent to use our quizzes and games. The evaluation showed that the use of digital games for learning purposes is not very common, neither at school nor at university, although the students had worked with such tools before. The students are also very interested in using and developing such digital games not only for their own study, but also for their future work at school. © 2022 The Authors. Published by American Chemical Society and Division of Chemical Education, Inc.

Implementation of an At-Home, First-Semester Biochemistry Lab Course: A Module Based on Banana Tyrosinase

This paper describes the development of a fully remote upper-class biochemistry lab course. The sudden change to online teaching in the middle of spring semester 2020 had a primarily negative impact on laboratory teaching. These effects were mitigated because the students had done many of the basic hands-on procedures before the switch. A true "at-home"biochemistry lab module was implemented in the fall semester of 2020 to ensure students could have a hands-on lab experience in a remote setting despite the remaining COVID-19 restrictions placed upon universities. The module covered several fundamental concepts and techniques found in a first semester biochemistry lab sequence: extraction and purification of a protein from a sample, and further analysis of the protein. Tyrosinase was isolated and purified from a banana extract followed by kinetic analysis of the enzyme. A key component to the module is an LED light board that, in combination with a cell-phone app, made a simple at-home colorimeter. The module was implemented in three sections of a first semester biochemistry lab course (81 students total) in the fall of 2020, and components of it have been used periodically since. Some of the procedures are now being implemented into normal in-lab sessions. An assessment in terms of a student survey showed that most of the students were able to adapt to this format and felt that their learning was not impeded. © 2022 American Chemical Society.

Navigating Analytical Chemistry Laboratories during COVID-19: Perspective of a Nigerian University

E-learning is not a new concept to the American University of Nigeria (AUN);however, it has always been applied to the lectures but not in the laboratories for the chemistry courses before and during the first phase of the COVID-19 lockdown. The sudden disruption of learning caused by the forced lockdown issued by the government authority in an attempt to curb the spread of the pandemic left most institutions of learning with unfinished syllabi as it occurred in the middle of the spring semester. Although some universities attempted to provide students with the lessons via remote classes, it was not without challenges, as the issuance met everyone unprepared. Hence, before the resumption of the Fall 2020 semester, the Petroleum chemistry department of AUN made it a point of duty to modify lab sessions to wedge against unforeseen circumstances such as pandemics that can cause an interruption to physical meetings. Herein we report a hybrid lab implementation in which physical lab meetings and virtual laboratories were combined alternately to cover a section of the lab scheme assigned for an analytical chemistry course. It aided our understanding of student reception and preference to the different learning styles and provided insight on alternatives to sustain learning amidst disruptions in normal learning structure by circumstances like the pandemic. © 2022 American Chemical Society and Division of Chemical Education, Inc.

Gamified Virtual Laboratory Experience for In-Person and Distance Students

This study explores the design and delivery of two gamified, virtual laboratories, created to replace or compliment the compulsory third-semester university chemistry laboratories. Due to the COVID-19 pandemic, laboratory experiments needed to be adapted to suit both on- and off-campus students. Here, we include detailed guidelines on how to produce and embed interactive videos into a 360° virtual tour, while also reflecting on the student feedback. This resource was used by both student groups, acting as a complete replacement for off campus students and as a complementary resource to those on-campus. All surveyed students agreed that the virtual laboratory was an effective learning aid, with both on- and off-campus students appreciating the slow-pace and theory focus. This delivery method shows promise as a beneficial tool for academics and students when adapting subject delivery in the age of open universities and distance learning. © 2022 American Chemical Society and Division of Chemical Education, Inc.

Student Perceptions of Remote Chemistry Laboratory Delivery Models

The COVID-19 pandemic of Spring 2020 saw chemistry instructors across the globe working to deliver traditional hands-on laboratory learning within a remote learning environment. This study focused on the student perspective on remote laboratory delivery models across 13 Fall 2020 chemistry courses with students from all four years of undergraduate study and varying declared majors. For those students who were able to experience in-person laboratory experiments, the majority indicated that they were of high value to their overall learning experience. Specifically, the students noted that the value of the in-person experiential laboratory learning was tied to their ability to learn and practice their technical skills while putting the theory learned in class into practical context and application. Remote laboratory alternatives in the form of video-recorded experiments and online simulations were seen to be less valuable to the overall student learning experience. While students indicated that they highly valued in-person laboratory experiences and would like to see them continually implemented within their learning experiences, careful design and implementation of remote alternatives may provide meaningful alternatives when in-person laboratory instruction is not possible or perhaps enhance already existing laboratory curricula.

Investigating Meaningful Learning in Virtual Reality Organic Chemistry Laboratories

Virtual reality (VR) lab experiences for organic chemistry were developed at NC State University as an accessibility tool for students who are unable to attend in-person laboratories due to disabilities, attendance challenges such as pregnancy or military deployment, or safety concerns. The resulting first-person VR experiences are immersive and realistic, with a virtual teaching assistant guiding the user along the steps required to complete the experiment, including feedback as needed. During the COVID pandemic, these laboratories replaced traditional face-to-face laboratories at NC State and several other universities. During the summer of 2020, we used the Meaningful Learning in the Laboratory Instrument (MLLI) to measure both the cognitive and affective dimensions of students' expectations of the virtual lab before the course and their experiences with virtual reality after completing the course. Students who completed virtual reality laboratories reported more positive affective experiences than they anticipated, including little frustration or confusion in the laboratory. © 2021 American Chemical Society and Division of Chemical Education, Inc.